SNX1 Polyclonal Antibody, 100ul Biomatrix Mutations in this gene cause

Mutations in this gene cause Wolf-Hirschhorn syndrome| a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4

Like other cytokine receptors

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved

SNX1 Polyclonal Antibody, 100ul Biomatrix Mutations in this gene causeSNX1 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Sorting nexin 1 regulates the cell surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease activated receptor 1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members.