p47-phox(Phospho Ser359) Polyclonal Antibody, 100ul Human Genome Knockout Libraries Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C

The protein encoded by this gene belongs to the Fbws class

A smaller fraction is cytoplasmic

100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31

p47-phox(Phospho Ser359) Polyclonal Antibody, 100ul Human Genome Knockout Libraries Alternatively spliced transcript variants encodingThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.