Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 50ul Transporters Members of the WIPI subfamily

Members of the WIPI subfamily of WD40 repeat proteins

Also see SRD5A2 (MIM 607306)

Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium

Genetic variations of this gene have been associated with Parkinson disease susceptibility

Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 50ul Transporters Members of the WIPI subfamilyThis gene encodes a DNA topoisomerase an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation chromatid separation and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another thus altering