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UBE2W Polyclonal Antibody, 20ul Stepper Binds TCF4 and RB1

SKU: 42595353823

4.7
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UBE2W Polyclonal Antibody, 20ul Stepper Binds TCF4 and RB1This gene encodes a nuclear localized ubiquitin conjugating enzyme (E2) that, along with ubiquitin activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple

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Description

Binds TCF4 and RB1

Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome

Diseases associated with MYSM1 include hemorrhagic cystitis

and contains a modular suppression domain that functions in the inhibition of transcription

UBE2W Polyclonal Antibody, 20ul Stepper Binds TCF4 and RB1This gene encodes a nuclear localized ubiquitin conjugating enzyme (E2) that, along with ubiquitin activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple

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