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GCM1 Rabbit Polyclonal Antibody, 20ul Bacterial Expression but down regulated in ovarian

SKU: 42767077263

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GCM1 Rabbit Polyclonal Antibody, 20ul Bacterial Expression but down regulated in ovarianThis gene encodes a DNA binding protein with a gcm motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM motif (A G)CCCGCAT a novel sequence among known targets of DNA binding proteins. The N terminal DNA binding domain confers the unique DNA binding activity of this protein.

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Description

but down regulated in ovarian cancer cell lines and primary carcinomas

Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas

Differential expression of this gene may be associated with progression of breast and prostate cancer

caudate putamen

GCM1 Rabbit Polyclonal Antibody, 20ul Bacterial Expression but down regulated in ovarianThis gene encodes a DNA binding protein with a gcm motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM motif (A G)CCCGCAT a novel sequence among known targets of DNA binding proteins. The N terminal DNA binding domain confers the unique DNA binding activity of this protein.

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