Phospho-Akt1 (Y474) Polyclonal Antibody, 100ul Cell Culture Flasks This protein localizes to the

This protein localizes to the peroxisomal membrane

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

Since both phosphorylation and glycosylation compete for similar serine or threonine residues

and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily

Phospho-Akt1 (Y474) Polyclonal Antibody, 100ul Cell Culture Flasks This protein localizes to theThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a