TNIK Polyclonal Antibody, 100ul Buffers & Solutions This gene is overexpressed in

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck

Multiple alternatively spliced transcript variants encoding the same protein have been found

PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection

Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation

TNIK Polyclonal Antibody, 100ul Buffers & Solutions This gene is overexpressed inGerminal center kinases (GCKs), such as TNIK, are characterized by an N terminal kinase domain and a C terminal GCK domain that serves a regulatory function (Fu et al., 1999