EEA1 Polyclonal Antibody, 50ul Drug Development and Evaluation Members of the F-box protein

Members of the F-box protein family| such as FBXL18| are characterized by an approximately 40-amino acid F-box motif

Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity

Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1

The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus

EEA1 Polyclonal Antibody, 50ul Drug Development and Evaluation Members of the F-box proteinBinds phospholipid vesicles containing phosphatidylinositol 3 phosphate and participates in endosomal trafficking.