EKLF Polyclonal Antibody, 50ul Culture Plate Inserts The protein encoded by CDC5L

The protein encoded by CDC5L (cell division cycle 5 like) shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product

Interacts with RINT1

Transgenic mice overexpressing this gene exhibit defects in testis

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

EKLF Polyclonal Antibody, 50ul Culture Plate Inserts The protein encoded by CDC5LKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.