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SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging This gene is broadly expressed

SKU: 43501421772

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SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging This gene is broadly expressedThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced

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Description

This gene is broadly expressed

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development

Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system

is not inhibited by warfarin

SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging This gene is broadly expressedThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced

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