CLN8 Polyclonal Antibody, 50ul Transporters cofactor:Binds 2 heme groups non-covalently

cofactor:Binds 2 heme groups non-covalently

SLC22A18 is imprinted

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

The protein encoded by this gene belongs to the leucine-rich repeat superfamily

CLN8 Polyclonal Antibody, 50ul Transporters cofactor:Binds 2 heme groups non-covalentlyThis gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER Golgi intermediate compartment. Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR), which is a subtype of neuronal ceroid lipofuscinoses