GPSM2 Polyclonal Antibody, 100ul In vitro Assessment Defects in this gene are

Defects in this gene are a cause of dwarfism| while hypersecretion of the encoded protein is a cause of gigantism

May play an active role in recombination processes in concert with other members of the RAD52 epistasis group

It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner

A pseudogene of this gene is located on the long arm of chromosome 14

GPSM2 Polyclonal Antibody, 100ul In vitro Assessment Defects in this gene areThe protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N terminal half of this protein contains 10 copies of leu gly asn (LGN) repeat, and the C terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and