SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 100ul Lysosome a repair-deficient mutant that exhibits

a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents

The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis

phosphorylates and activates LIM kinase

PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator)

SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 100ul Lysosome a repair-deficient mutant that exhibitsThis gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b together with splicing factor 3a and a 12S RNA unit forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b 3a complex binds pre mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre mRNA. Splicing factor 3b is also a component of the minor U12 type spliceosome. The