Bovine Caspase 3, CASP3 ELISA Kit , 96T Supplements two paralogs of the yeast

two paralogs of the yeast protein have been identified

and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7)

Multiple transcript variants encoding different isoforms have been found for PPP1R1B

The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene

Bovine Caspase 3, CASP3 ELISA Kit , 96T Supplements two paralogs of the yeastInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.