MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene result

Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis

This gene encodes a nuclear protein involved in homologous recombination

Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family

An important paralog of this gene is AVPR1B

MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene resultThis gene encodes a member of the P type lectin family. P type lectins play a critical role in lysosome function through the specific transport of mannose 6 phosphate containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene