Raf-1(Phospho Ser642) Polyclonal Antibody, 50ul sgRNA customized design The encoded protein homodimerizes and

The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex

a disorder resulting in neuropathy

a soluble form (S-COMT) and a membrane-bound form (MB-COMT)

Proteolysis also occurs by way of CUL-4 associating with Nedd-8

Raf-1(Phospho Ser642) Polyclonal Antibody, 50ul sgRNA customized design The encoded protein homodimerizes andThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.