DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy The encoded protein (A-kinase anchoring

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

CCT8 encodes the theta subunit of the CCT chaperonin

The serine/threonine-protein kinase tousled-like 2 is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone

Two pseudogenes of this gene have been identified within this cluster on chromosome 7

DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy The encoded protein (A-kinase anchoringThe protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.