SEN2 Polyclonal Antibody, 20ul Modified Oligos hereditary hemorrhagic telangiectasia and erythropoietic

hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18

a heavy catalytic subunit and a light regulatory subunit

The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm)

cerebellar Purkinje cells

SEN2 Polyclonal Antibody, 20ul Modified Oligos hereditary hemorrhagic telangiectasia and erythropoieticThis gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.