Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization This gene encodes a glycosylated

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif| two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors| one CHARLIE8 transposable element-like sequence| and a BED zinc finger

Alternative splicing has been observed in this gene

Component of a mSin3A corepressor complex that contains SIN3A| SAP130| SUDS3/SAP45| ARID4B/SAP180| HDAC1 and HDAC2

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization This gene encodes a glycosylatedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).