Human Uromodulin, UMOD ELISA Kit, 96T Vessels Delivers inhibitory signals upon binding

Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed: 21276005)

glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule

This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis

PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes

Human Uromodulin, UMOD ELISA Kit, 96T Vessels Delivers inhibitory signals upon binding[Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL 1, IL 2) and TNF (PubMed: 3$498. 00 $360. 00215). Facilitates neutrophil migration across renal