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CD1 Monoclonal Antibody(9H6), 50ul Contamination Detection & Removal Chromosomal translocation of this locus

SKU: 45921830500

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CD1 Monoclonal Antibody(9H6), 50ul Contamination Detection & Removal Chromosomal translocation of this locusThis gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta 2 microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are

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Description

Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias

Altered levels of this protein have been reported in cancers of different organs

Unlike other members of the ADAM protein family| the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif

The heat shock protein family B (small) member 6 likely plays a role in smooth muscle relaxation

CD1 Monoclonal Antibody(9H6), 50ul Contamination Detection & Removal Chromosomal translocation of this locusThis gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta 2 microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are

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