FBX46 Rabbit Polyclonal Antibody, 50ul Enzymes conotruncal heart defects and facial

conotruncal heart defects and facial dysmorphology

Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed

resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production

RIN1 (Ras interaction/interference) was identified as a Ras-interacting protein in yeast

FBX46 Rabbit Polyclonal Antibody, 50ul Enzymes conotruncal heart defects and facialMembers of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004