SELV Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Mutations in TP63 are associated

Mutations in TP63 are associated with ectodermal dysplasia

Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex

Defects in this gene are a cause of autosomal dominant cutis laxa

Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release

SELV Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Mutations in TP63 are associatedThis gene encodes a selenoprotein which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem loop structure the sec insertion sequence (SECIS) that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.