MEK-1/2 Polyclonal Antibody, 100ul[BT-AP05343] Cell Separation and Collection Mutations in KAL1 cause the

Mutations in KAL1 cause the X-linked Kallmann syndrome

Lys-29 and Lys-48-linked ubiquitin chains (in vitro) (PubMed: 24724799)

while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site

The encoded protein may also have roles in organogenesis and during adulthood

MEK-1/2 Polyclonal Antibody, 100ul[BT-AP05343] Cell Separation and Collection Mutations in KAL1 cause theDual specificity mitogen activated protein kinase kinase 2 encoded by MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. Dual specificity mitogen activated protein kinase kinase 2 is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP