RND2 Polyclonal Antibody, 20ul Cell Separation and Collection A second breast cancer susceptibility

A second breast cancer susceptibility gene

It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML

TAF1 is part of a complex transcription unit (TAF1/DYT3)

It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence| duration| and/or severity of chemotherapy induced cytopenias

RND2 Polyclonal Antibody, 20ul Cell Separation and Collection A second breast cancer susceptibilityThis gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast ovarian cancer susceptibility gene BRCA1.