p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer Crafted for ultra-high performance

Crafted for ultra-high performance

and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E

It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors

Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production

p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer Crafted for ultra-high performanceThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.