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Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Streamline your experiments with precision

SKU: 4666624793

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Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Streamline your experiments with precisionAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent

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Description

Streamline your experiments with precision and ease

Aberrant splice variants expressed in tumor cell lines have also been described

and can interact with other proteins

a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules

Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Streamline your experiments with precisionAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent

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