Smad3 Polyclonal Antibody, 20ul[BT-AP08387] Proteases Mutations in this gene have

Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2

Inherited mutations in BRCA1 and this gene

The protein probably associates with the 5S rRNA

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

Smad3 Polyclonal Antibody, 20ul[BT-AP08387] Proteases Mutations in this gene haveMothers against decapentaplegic homolog 3 encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a