SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 100ul Sealing Film CAV2 and related family member

CAV2 and related family member (CAV1) are located next to each other on chromosome 7

including those that are involved in familial adenomatous polyposis

The alpha chain is approximately 33-35 kDa and its gene contains 5 exons

a disease characterized by heart defects

SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 100ul Sealing Film CAV2 and related family memberThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in