PGFRL Polyclonal Antibody, 100ul Insect Expression NBPF1 is a member of

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3)

Rare transcript variants have been reported for this gene

The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2

PGFRL Polyclonal Antibody, 100ul Insect Expression NBPF1 is a member ofThis gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non small cell lung cancers. This suggests this gene product may function as a tumor suppressor.