IDI1 Rabbit Polyclonal Antibody, 20ul Liquid Handling Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants which encode the same protein

Five alternatively spliced transcript variants encoding distinct isoforms have been reported

Hyperphosphorylation of Rb proteins results in a loss of E2F binding and allows for transcriptional activation and cell cycle progression

which contains two zinc finger motifs that are required for hetero- or homo-dimerization

IDI1 Rabbit Polyclonal Antibody, 20ul Liquid Handling Alternative splicing of this geneIDI1 encodes a peroxisomally localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is