OSBL1 Rabbit Polyclonal Antibody, 20ul Protein Expression subcellular location:Colocalizes with activated RAC3

subcellular location:Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia

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the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)

characterized by the signature 7-transmembrane domain motif

OSBL1 Rabbit Polyclonal Antibody, 20ul Protein Expression subcellular location:Colocalizes with activated RAC3This gene encodes a member of the oxysterol binding protein (OSBP) family a group of intracellular lipid receptors. Most members contain an N terminal pleckstrin homology domain and a highly conserved C terminal OSBP like sterol binding domain although some members contain only the sterol binding domain. Transcript variants derived from alternative promoter usage and or alternative splicing exist; they encode different isoforms.