Rat Intercellular Adhesion Molecule 1, ICAM-1 ELISA Kit, 96T Human Genome Knockout Libraries The product of this gene

The product of this gene belongs to the ligand-gated ion channel receptor superfamily

It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function

The presence of the J domain defines a protein as a member of the DnaJ family

which act as platforms for receptor clustering and signaling

Rat Intercellular Adhesion Molecule 1, ICAM-1 ELISA Kit, 96T Human Genome Knockout Libraries The product of this geneICAM proteins are ligands for the leukocyte adhesion protein LFA 1 (integrin alpha L beta 2). During leukocyte trans endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26 SGEF and RHOG activation (By similarity).