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Repac Polyclonal Antibody, 100ul Pipette Controller The first mRNA transcript isolated

SKU: 47547127015

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Repac Polyclonal Antibody, 100ul Pipette Controller The first mRNA transcript isolatedMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5 (Rap guanine nucleotide exchange factor 5), serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation.

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Description

The first mRNA transcript isolated for GCFC2 (GC-rich sequence DNA-binding factor 2) was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204)

|miscellaneous:Contrarily to other members of the family that can bind several FGF receptors FGF19 is specific for FGFR4

other diseases resulting in hair loss

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

Repac Polyclonal Antibody, 100ul Pipette Controller The first mRNA transcript isolatedMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5 (Rap guanine nucleotide exchange factor 5), serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation.

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