H2AZ Polyclonal Antibody, 50ul Thermal Control Male mice with mutations in

Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

Three transcript variants encoding two different isoforms have been found for POLR2E

Structural similarity of ULK1/2 has also been recognized with the yeast autophagy protein Atg1/Apg1

H2AZ Polyclonal Antibody, 50ul Thermal Control Male mice with mutations inHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.