c-Fos(Phospho Ser32) Polyclonal Antibody, 50ul 3D Cell Culture Consumables Genome-wide association studies in human

Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity

The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins

followed by two fibronectin type-III motifs

Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome

c-Fos(Phospho Ser32) Polyclonal Antibody, 50ul 3D Cell Culture Consumables Genome-wide association studies in humanThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.