TPH1 Polyclonal Antibody, 100ul[BT-AP09150] Bio-Reaction Tube Frequent amplification of this gene

Frequent amplification of this gene has been found in human tumors

and is used as a fluorescent tracer in trasfection and transgenic experiments

This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division

This encoded protein contains a GRIP domain which is thought to be used in targeting

TPH1 Polyclonal Antibody, 100ul[BT-AP09150] Bio-Reaction Tube Frequent amplification of this geneTPH1 (tryptophan hydroxylase 1) encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and