LATS1/2(Phospho-Ser909) Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges |PTM:Phosphorylated on Tyr-198 and Tyr-220

|PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity)

and malignant cells of bone and soft tissue sarcomas

May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes

May be one regulator of transcriptional events during hemopoietic development

LATS1/2(Phospho-Ser909) Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges |PTM:Phosphorylated on Tyr-198 and Tyr-220The protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative