CD6 Polyclonal Antibody, 50ul[BT-AP02057] Apoptosis & Autophagy Defects in this gene are

Defects in this gene are the cause of immunodeficiency polyendocrinopathy

The protein consists of an amino-terminal 7S domain

which impairs its recruitment to the TCR and subsequent activation

This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1

CD6 Polyclonal Antibody, 50ul[BT-AP02057] Apoptosis & Autophagy Defects in this gene areCofilin 1 encoded by CFL1 can polymerize and depolymerize F actin and G actin in a pH dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin modulating protein that binds and depolymerizes filamentous F actin and inhibits the polymerization of monomeric G actin in a pH dependent manner. It is involved in the