NOC2L Polyclonal Antibody, 50ul Antibody Development It is thought to regulate

It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB)

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17

RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif

This protein contains 6 WD repeats and is highly expressed in the heart

NOC2L Polyclonal Antibody, 50ul Antibody Development It is thought to regulateHistone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al. 2005 [PubMed 16322561]).