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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patients

SKU: 49572680560

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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patientsTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

as described in human patients with lissencephaly

Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein

The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits

The transcript for this particular family member uses more than one polyadenylation site

A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patientsTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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