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MPO Polyclonal Antibody, 100ul Molecular Biologyn At least three alternatively spliced

SKU: 49594422254

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MPO Polyclonal Antibody, 100ul Molecular Biologyn At least three alternatively splicedMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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Description

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

hemostasis

the C-terminal kinase domain binds to its own N-terminal region

MPO Polyclonal Antibody, 100ul Molecular Biologyn At least three alternatively splicedMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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