Caspase-8 Monoclonal Antibody(2G12), 50ul Pipette Micro Tips This gene is part of

This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21

Mutations in NME1 have been identified in aggressive neuroblastomas

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

|Belongs to the intercrine alpha (chemokine CxC) family

Caspase-8 Monoclonal Antibody(2G12), 50ul Pipette Micro Tips This gene is part ofThis gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large