Rhophilin Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Defects in this protein have

Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14)

Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

this protein is thought to be involved in translation

Rhophilin Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Defects in this protein haveHas no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.