Synuclein-Beta Polyclonal Antibody, 50ul Antibody Humanization Binds to| and stabilizes MAP3K6

Binds to| and stabilizes MAP3K6 and is activated by MAP3K6 by phosphorylation on Thr-838

The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking

This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis

thought to form the base of the dynein arm

Synuclein-Beta Polyclonal Antibody, 50ul Antibody Humanization Binds to| and stabilizes MAP3K6SNCB encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The Beta synuclein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants.