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ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as a

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ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as aThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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Description

this protein functions as a regulator of the pre-mRNA splicing process

which consists of an eight-stranded parallel α/β structure

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity| and therefore is known as a dual specificity phosphatase

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as aThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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