TH Polyclonal Antibody, 50ul[BT-AP08988] Protein Analysis SPINK5 encodes a multidomain serine

SPINK5 encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains

and are represented as GeneID: 348249

The protein is a component of the nuclear matrix during the G2 phase of interphase

It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML

TH Polyclonal Antibody, 50ul[BT-AP08988] Protein Analysis SPINK5 encodes a multidomain serineTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.