PLP2 Rabbit Polyclonal Antibody, 20ul Gel & Buffers Members of this family encode

Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins

|tissue specificity:Expressed in fetal brain| cartilage| retina| and adult gall bladder

Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes| dendritic cells| macrophages)

This gene may play a role in the progression of several malignancies including melanoma

PLP2 Rabbit Polyclonal Antibody, 20ul Gel & Buffers Members of this family encodeThis gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X linked mental retardation. A pseudogene of this gene is found on chromosome 5.