ERK 8(Phospho Thr175/Y177) Polyclonal Antibody, 50ul Bio-Reaction Tube Alternative splicing of this gene

Alternative splicing of this gene generates 2 transcript variants

Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation

All channels within the cell culture system are large in size

There are at least two protein isoforms of the Double C2 protein| namely alpha (DOC2A) and beta (DOC2B)| which contain two C2-like domains

ERK 8(Phospho Thr175/Y177) Polyclonal Antibody, 50ul Bio-Reaction Tube Alternative splicing of this geneCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,The N terminal region (1 20) is the minimal region necessary for ubiquitination and further proteosomal degradation.,The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation: Activated by threonine and tyrosine phosphorylation. Inhibited by dual specificity phosphatases, such as DUSP1.,In vitro, phosphorylates MBP.,PTM: