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Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series GO annotations related to this

SKU: 51209462037

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Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series GO annotations related to thisERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

GO annotations related to this gene include chromatin binding

This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation

Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR)

This kinase binds to TRAF2 and stimulates NF-kappaB activity

Neu Polyclonal Antibody, 50ul[BT-AP05904] PCR Series GO annotations related to thisERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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